Begin by heating olive oil in a large skillet over low heat. Sauté the minced shallots and onions gently until fragrant and translucent. This creates a flavorful base for your sauce. Sprinkle a little salt to help them release moisture and soften evenly.
Add the garlic and cook for another 1–2 minutes, stirring occasionally to avoid burning. If the pan looks dry, add a touch more olive oil. Stir in the crushed red pepper, garlic powder, Old Bay, and black pepper to start building the flavor layers.
Now toss in the cherry tomatoes. Season with a bit more salt and sauté for about a minute until the tomatoes start softening slightly. They’ll burst a little in the sauce later, adding natural sweetness and acidity.
Raise the heat to medium and pour in the white wine. Let it simmer for 2–3 minutes so the alcohol can cook off and the flavors concentrate. Taste the sauce at this point and adjust the salt as needed. You want the liquid to be slightly reduced and fragrant.
Lightly season the shrimp with Old Bay, garlic powder, and a pinch of pepper. Add them to the pan along with mussels, chopped parsley, and butter. Cover the skillet and let the seafood cook for 3–4 minutes until the mussels open and the shrimp turns pink and opaque.
Once cooked, remove the shrimp and mussels and set them aside on a plate. This prevents overcooking while the pasta finishes. Reduce the heat back to low and keep the sauce gently simmering.
Cook your angel hair pasta in salted water until al dente (about 2–3 minutes). Before draining, scoop out about ½ cup of the pasta water. Add the drained pasta to the sauce and pour in the pasta water to help bind the sauce and coat the noodles evenly.
Stir in freshly grated parmesan until it melts and the sauce clings to the pasta. Turn off the heat once most of the liquid has absorbed. The texture should be creamy and glossy without being soupy.
Squeeze in fresh lemon juice and give the pasta a final toss to brighten all the flavors. Plate the pasta and top it with the reserved shrimp and mussels. Garnish with extra parsley, a sprinkle of parmesan, and crushed red pepper.